I blogged about this before - if you have issues with some Office client-MOSS integration within a VPC you should try net stop sens. But what does it do behind the scenes?
Apparently it stops the System Event Notification service which is tracks system events such as Windows logon, network, and power events. It will also notify COM+ Event System subscribers of these events (such as a lot of client apps) in a real world distributed environment. Off course when you are not on a network it is kind of useless and more of hassle as you may have noticed.